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AFIRSTCHOICE* JAN/FEB, 2021 FOR OA AND BACK PAIN RELIEF.1,2 Start with Nurofen 400 Double Strength for powerful pain relief1-5 Nurofen 400 Double Strength provides the powerful pain relief of a single-active NSAID for up to 8 hours in one tablet,3–5 with the same low risk of GI side effects as paracetamol.^6–8 Step up to Nuromol for dual-action pain relief 9 Nuromol offers strong 8-hourly over- the- counter pain relief in one tablet.3,9 Step up to a combination of two actives that’s as well tolerated as the single active ingredients alone.^3 New Liquid Caps Coming Soon *Ibuprofen is a first-line oral pharmacotherapy for osteoarthritis flare-up pain and low back pain.1,2 ^When taken as directed in an over-the-counter setting in people without contraindications/precautions. GI: gastrointestinal. NSAID: non-steroidal anti-inflammatory drug. OA: osteoarthritis. Nurofen 400 Double Strength contains 400mg ibuprofen. For the temporary relief of pain. Nuromol contains 200 mg ibuprofen and 500 mg paracetamol. For the temporary relief of pain and inflammation. References: 1. Royal Australian College of General Practitioners. Guideline for the treatment of knee and hip osteoarthritis, 2018. 2. Therapeutic Guidelines. Rheumatology. Low back pain, August 2020. 3. Mehlisch DR, et al. Clin Ther 2010;32(6):1033-1049. 4. Malmstrom K, et al. Clin Ther 1999;21(10):1653-1663. 5. Malmstrom K, et al. Clin Ther 2004;26(5):667-679. 6. Moore N, et al. Clin Drug Invest 1999;18:89–98. 7. Rampal P, et al. J Int Med Res 2002;30:301–308. 8. Varrassi G, et al. Adv Ther 2019; doi: 10.1007/s12325-019-01144-9. 9. Moore RA, et al. Cochrane Datab Syst Rev 2015;11:CD010794. ®NUROFEN is a registered trademark of the Reckitt Benckiser Group of Companies. Level 47, 680 George St, Sydney 2000, NSW Australia. Prepared December 2020.