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42 THE PHARMACY STATE OF THE INDUSTRY REPORT Top 5 Molecules by Value DENOSUMAB BARICITINIB TOCILIZUMAB ABATACEPT RISEDRONIC ACID Top Molecule Growth QRT vs same QRT LY DENOSUMAB BARICITINIB TOCILIZUMAB ABATACEPT RISEDRONIC ACID Ranked by value of change DENOSUMAB BARICITINIB TOCILIZUMAB RISEDRONIC ACID MELOXICAM Top 5 Corporate % Shares (Wholesale) AMGEN LILLY ROCHE BRISTOLMYER SQUIBB THERAMEX AUSTRALIA PTY LTD Value ($) $58,052,524 $10,665,583 $9,616,064 $7,241,733 $4,461,347 Value Change (%) 20% 134% 28% 4% 18% Value Change (%) Volume (units) 217,295 8,743 18,018 26,891 177,996 Volume change (%) 21% 134% 8% -12% 18% Volume change (%) OMALIZUMAB Top 5 Corporate % Shares (Wholesale) $3,037,658 61% Value ($) $71,271,525 $28,485,235 $26,060,277 $9,731,705 $8,033,227 59% Volume (units) 1,590,886 559,802 819,599 253,522 19,519 Value of change ($) $9,713,373 $6,115,381 $2,076,829 $289,605 $666,559 Value of change ($) $9,713,373 $6,115,381 $2,076,829 $666,559 $523,286 Pharmacy Volume Volume Change Value of change ($) $2,424,174 -$2,861,284 $9,942,680 $2,050,997 $1,669,189 Value of change ($) $9,942,680 $3,878,225 $3,618,762 $3,228,843 $2,719,729 Pharmacy Volume Volume Change GLAXOSMITHKLINE BOEHRINGER INGELHM ASTRAZENECA CIPLA NOVARTIS SENSORY ORGANS Pharmacy Value Value Change Top 5 Molecules by Value AFLIBERCEPT RANIBIZUMAB BIMATOPROST + TIMOLOL LATANOPROST DEXAMETHASONE $168,919,108 13% Pharmacy Volume Volume Change Value of change ($) $10,570,124 $4,418,732 $456,733 $256,222 $1,017,859 Value of change ($) $10,570,124 $4,418,732 $1,017,859 $456,733 $425,579 2,247,012 15% 20% 21% 134% 134% 28% 8% 18% 18% 21% 23% Value ($) Volume $58,052,524 217,295 $10,665,583 8,743 $10,480,548 147,219 $7,241,733 26,891 $4,118,067 163,698 (units) Top Molecule Growth QRT vs same QRT LY AFLIBERCEPT RANIBIZUMAB BIMATOPROST + TIMOLOL LATANOPROST DEXAMETHASONE Ranked by value of change AFLIBERCEPT RANIBIZUMAB DEXAMETHASONE BIMATOPROST + TIMOLOL CIPROFLOXACIN Top 5 Corporate % Shares (Wholesale) BAYER PHARMA NOVARTIS ALLERGAN UPJOHN MUNDIPHARMA Value ($) $91,964,000 $49,080,475 $2,405,806 $2,244,564 $2,127,514 Value Change (%) 13% 10% 23% 13% 92% Value Change (%) 13% 10% 92% 23% 87% Value ($) $91,964,000 $59,443,566 $9,420,684 $3,267,184 $1,326,264 Volume (units) 87,243 48,968 88,007 363,989 84,342 Volume change (%) 13% 10% 24% 19% 12% Volume change (%) 13% 10% 12% 24% -5% Volume (units) 87,243 606,842 471,598 437,363 141,506 NERVOUS SYSTEM Pharmacy Value Value Change Top 5 Molecules by Value FINGOLIMOD PREGABALIN CLADRIBINE ARIPIPRAZOLE PALIPERIDONE PALMITATE $419,986,402 16% 28,155,755 22% Top Molecule Growth QRT vs same QRT LY FINGOLIMOD PREGABALIN CLADRIBINE ARIPIPRAZOLE PALIPERIDONE PALMITATE Ranked by value of change CLADRIBINE AGOMELATINE LISDEXAMFETAMINE GUANFACINE MELATONIN Top 5 Corporate % Shares (Wholesale) NOVARTIS MUNDIPHARMA JANSSEN CILAG APOTEX MYLAN AUSTRALIA RESPIRATORY SYSTEM Value ($) $32,912,194 $23,449,319 $18,385,592 $15,121,065 $14,952,379 Value Change (%) 8% -11% 118% 16% 13% Value Change (%) 118% 66% 47% 148% 41% Value ($) $44,455,176 $30,458,534 $30,239,744 $27,912,498 $25,932,706 Volume (units) 15,466 1,076,392 1,223 92,330 38,621 Volume change (%) 8% 22% 113% 25% 9% Volume change (%) 113% 26% 47% 148% 40% Volume (units) 342,611 1,396,965 399,938 5,144,282 5,664,189 Pharmacy Value Value Change Top 5 Molecules by Value $167,886,689 47% 4,031,624 51% FLUTICASONE + SALMETEROL BUDESONIDE + FORMOTEROL TIOTROPIUM BROMIDE FLUTICASONE FUROATE + VILANTEROL FLUTICASONE FUROATE + UMECLIDINIUM BROMIDE + VILANTEROL Value ($) $34,426,029 $24,848,193 $14,001,567 $11,497,460 $10,109,415 Value Change (%) 58% 67% 1% 62% 121% Value Change (%) 58% 67% 121% 62% Volume (units) 740,444 742,786 416,549 212,883 117,524 Volume change (%) 53% 73% 24% 61% 121% Volume change (%) 53% 73% 121% 61% Top Molecule Growth QRT vs same QRT LY FLUTICASONE + SALMETEROL BUDESONIDE + FORMOTEROL TIOTROPIUM BROMIDE FLUTICASONE FUROATE + VILANTEROL FLUTICASONE FUROATE + UMECLIDINIUM BROMIDE + VILANTEROL Ranked by value of change FLUTICASONE + SALMETEROL BUDESONIDE + FORMOTEROL FLUTICASONE FUROATE + UMECLIDINIUM BROMIDE + VILANTEROL FLUTICASONE FUROATE + VILANTEROL Value of change ($) $12,577,312 $9,935,094 $164,122 $4,378,940 $5,540,402 Value of change ($) $12,577,312 $9,935,094 $5,540,402 $4,378,940 RETAIL PHARMACY • JUL 2020