Page 18 - rp-may-2020

NSAID:
non-steroidal anti-inflammatory drug.y drug.
OA:
osteoarthritis.thritis.
References:
1.
Kielly J, Davis EM and Marra C Marra C
Can Pharm J (Ott)m J (Ott)
2017;150(3):156–68. Sokolove S, Lepus CM.
2.
Sokolove S, Lepus CM.
Ther Adv Musculoskel DisDis
2013;5(2):77–
94. The Royal Australian College of General Practitioners. Guideline for the management of knee and hip osteoarthritis. 2nd edn. East Melbourne, Vic:
3.
The Royal Australian College of General Practitioners. Guideline for the management of knee and hip osteoarthritis. 2nd edn. East Melbourne, Vic:
RACGP, 2018., 2018.
4.
Therapeutic Guidelines. Introduction to osteoarthritis. eTG December 2019 edition. Australian Government. Department of Health. Modified thritis. eTG December 2019 edition. Australian Government. Department of Health. Modified
5.
release paracetamol Available at: https://www.tga.gov.au/modified-release-paracetamol (accessed 14 January 2020). Moore RA vailable at: https://www.tga.gov.au/modified-release-paracetamol (accessed 14 January 2020). Moore RA
6.
et al. Cochr Data Syst Rev
2015;11. Art No.: CD010794. Moore RA t No.: CD010794. Moore RA
7.
et al. Clin Drug Invest
1999;18(2):89-98. Rampal P Rampal P
8.
et al. J Int Med Res
2002;30:301–308. Varrassi G Varrassi G
9.
et al.
Adv Ther
2019; doi: 10.1007/s12325-019-01144-9. Susko AM and Fitzgerald GK,
10.
Susko AM and Fitzgerald GK,
Open Access Rheumatol
2013;5:81–91.
Reckitt Benckiser (Australia) Pty Ltd. Level 47, 680 George St, Sydney 2000, NSW Australia. Prepared
Februaryy
2020. RB0056.
Find the right balance of pain relief for flare-ups
1
* 4 out of 10 of patients achieved at least 50% pain relief with either ibuprofen 400mg or diclofenac 25mg. Graph adapted from a Cochrane review of 21 different pain r diclofenac 25mg. Graph adapted from a Cochrane review of 21 different pain
relief medications. Not all medications shown. ^When taken as directed in an over-the-counter setting in patients without contraindications/precautions. Not all medications shown. ^When taken as directed in an over-the-counter setting in patients without contraindications/precautions.
6
ADVERTORIALTORIAL
HOW CAN YOU KEEP PATIENTS WITH OA ATIENTS WITH OA
MOVING IN THE RIGHT DIRECTION?
GUIDELINE RECOMMENDATIONS FOR PAIN RELIEF HAVE CHANGEDTIONS FOR PAIN RELIEF HAVE CHANGED
3
Plus, modified release
paracetamol is to be
upscheduled due to risks
associated with misuse
5
YOU NEED TO HELP PATIENTS ATIENTS
FIND A BALANCE
Between ‘just enough to enable movement and
not too much to cause adverse effects’fects’
1
0
50
% patients
ibuprofen 400mg
diclofenac 25mg
SIMILAR SUCCESS RATE TE
in pain relief vs diclofenac 25mg of GI side-effects as paracetamol
6*
SAME LOW RISK
of GI side-effects as paracetamol
7-9^
No recommendation
for or against paracetamol
3
(very low evidence)
Conditional recommendation
for oral NSAIDs
3
(moderate evidence)
GI events (dyspepsia)
4%
IBUPROFEN
VS
5.3%
PARACETAMOLAMOL
6
JUNE 2020
1
INFLAMMATION IS A CAUSE OF TION IS A CAUSE OF
OA PAIN AND PATHOLOGYAIN AND PATHOLOGY
2
Movement and exercise
are still most importanttant
3
BENEFITS THE MIND & BODY
4
HELP BREAK THE CYCLE OF PAIN:AIN:
4,10
REVIEW RECOMMEND & REFER FOR MULTIDISCIPLINARY CARE MONITOR RECOMMEND & REFER FOR MULTIDISCIPLINARY CARE MONITOR
NSAID:
non-steroidal anti-inflammator
OA:
osteoar
References:
1.
Kielly J, Davis EM and
Can Phar
2017;150(3):156–68.
2.
Ther Adv Musculoskel
2013;5(2):77–
94.
3.
RACGP
4.
Therapeutic Guidelines. Introduction to osteoar
5.
release paracetamol A
6.
et al. Cochr Data Syst Rev
2015;11. Ar
7.
et al. Clin Drug Invest
1999;18(2):89-98.
8.
et al. J Int Med Res
2002;30:301–308.
9.
et al.
Adv Ther
2019; doi: 10.1007/s12325-019-01144-9.
10.
Open Access Rheumatol
2013;5:81–91.
Reckitt Benckiser (Australia) Pty Ltd. Level 47, 680 George St, Sydney 2000, NSW Australia. Prepared
Februar
2020. RB0056.
Find the right balance of pain relief for flare-ups
1
* 4 out of 10 of patients achieved at least 50% pain relief with either ibuprofen 400mg o
relief medications.
6
ADVER
HOW CAN YOU KEEP P
MOVING IN THE RIGHT DIRECTION?
GUIDELINE RECOMMENDA
3
Plus, modified release
paracetamol is to be
upscheduled due to risks
associated with misuse
5
YOU NEED TO HELP P
FIND A BALANCE
Between ‘just enough to enable movement and
not too much to cause adverse ef
1
0
50
% patients
ibuprofen 400mg
diclofenac 25mg
SIMILAR SUCCESS RA
in pain relief vs diclofenac 25mg
6*
SAME LOW RISK
7-9^
No recommendation
for or against paracetamol
3
(very low evidence)
Conditional recommendation
for oral NSAIDs
3
(moderate evidence)
GI events (dyspepsia)
4%
IBUPROFEN
VS
5.3%
PARACET
6
JUNE 2020
1
INFLAMMA
OA P
2
Movement and exercise
are still most impor
3
BENEFITS THE MIND & BODY
4
HELP BREAK THE CYCLE OF P
4,10
REVIEW