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When it comes to treating OA flare-up pain with oral therapy, start with balanced pain relief.1-7 Nurofen 400 Double Strength offers the same low risk of GI side effects as paracetamol^5-7 with the powerful pain relief of an NSAID for up to 8 hours, in just 1 tablet.2-4 MAKE THE MOVE TO NUROFEN ^When taken as directed in an over-the-counter setting in people without contraindications/precautions. GI: gastrointestinal. OA: osteoarthritis. NSAID: non-steroidal anti-inflammatory drug. Nurofen 400 Double Strength contains 400mg ibuprofen. For the temporary relief of pain. References: 1. The Royal Australian College of General Practitioners. Guideline for the management of knee and hip osteoarthritis. 2nd edn. East Melbourne, Vic: RACGP, 2018. 2. Mehlisch DR et al. Clin Ther 2010;32(6):1033-1049. 3. Malmstrom K et al. Clin Ther 1999;21(10):1653- 1663. 4. Malmstrom K et al. Clin Ther 2004;26(5):667-679. 5. Moore N et al. Clin Drug Invest 1999;18:89–98. 6. Rampal P et al. J Int Med Res 2002;30:301–308. 7. Varrassi G et al. Adv Ther 2019; doi: 10.1007/s12325-019-01144-9. ®NUROFEN is a registered trademark of the Reckitt Benckiser Group of Companies. Level 47, 680 George St, Sydney 2000, NSW Australia. Prepared February 2020. FIRST-LINE FOR A REASON1